Route 66 Road Trip to Weatherford, Oklahoma

Historic Route 66 sign in Weatherford, Oklahoma

"The Mother Road" was established on November 11, 1926, and ultimately stretched 2,448 miles from Chicago to Santa Monica, California.

U.S. Route 66 was one of the United State's first continuous stretches of paved highway, and served as a major path for those who migrated west.

In Oklahoma, Route 66 covered 432 miles. After traveling through Illinois, Missouri and Kansas, the Mother Road entered Oklahoma near Commerce, and headed southwest to Miami, Catoosa, Tulsa, Sapulpa, Oklahoma City and into Weatherford.

From Weatherford, Route 66 continued west to Clinton, Elk City, Erick and into Texas.

Weatherford, Oklahoma

The City of Weatherford is located in Custer County, an hour west of Oklahoma City and east of Clinton. It was initially located on State Highway 3 starting in the early 1920s, which was redesignated as U.S. Route 66 in 1926 and paved entirely across Western Oklahoma by 1932.

Route 66, which followed Main Street through Weatherford, was lined with various tourist-oriented businesses including cafes, motels and gasoline stations.

Today, Weatherford is home to over 12,000 residents. Among its attractions are the Stafford Air & Space Museum, the Oklahoma Heartland of America Museum, the Weatherford Wind Energy Park, several city parks, golf courses and much more.

Weatherford also is the locale of Southwestern Oklahoma State University.

Lucille’s Roadhouse Diner at 1301 N Airport Road in Weatherford is a Route 66 styled restaurant with connections to the original Lucille's in nearby Hydro.

Map of Historic Route 66 in Oklahoma showing the location of Weatherford
Map of Historic Route 66 in Oklahoma showing the location of Weatherford

Stafford Air & Space Museum

The Stafford Air & Space Museum is named in honor of Weatherford native and legendary test pilot and astronaut, Lt. General Thomas P. Stafford. The museum is considered one of the finest and most comprehensive air and space museums in the central United States and encompasses 63,000 sq. ft. of exhibits under one roof!

The museum is located along Route 66 at I-40 and Exit 84 in Weatherford, and welcomes visitors seven days a week, 360 days a year.

Stafford Air & Space Museum website

General Thomas P. Stafford  Air and Space Museum in Weatherford, Oklahoma

Oklahoma Heartland of America Museum

The Heartland of America Museum offers visitors an opportunity to see many artifacts from the late 1800s through the 1950s in major historical exhibits. 

The 12,000 square foot main building is located on the southeast edge of Weatherford and is readily visible from Interstate 40 between exits 82 and 84. In addition to the main exhibit building, the Museum features three historic theme buildings on the grounds.

Oklahoma Heartland of America Museum website

General Thomas P. Stafford  Air and Space Museum in Weatherford, Oklahoma

McPhetridge Centennial Park

The City of Weatherford has eleven parks containing over eight hundred acres with many picnic and play areas. McPhetridge Centennial Park is located on the northwest corner of West Main (Route 66) and Broadway in downtown Weatherford.

Centennial Park in Weatherford, Oklahoma

Weatherford Wind Energy Park

Located across from the Weatherford City Hall, the park features an actual windmill blade, 122 feet long, from a wind turbine, along with a brief description of the wind energy industry.

A windmill blade mural is located in the park, at 501-599 West Rainey Avenue.

The windmill blade mural in Weatherford, Oklahoma

Lucille's Service Station and Roadhouse in Hydro, Oklahoma

Vintage 1945 Oklahoma license plate

Lucille's Service Station, a classic gas station built in 1929 along Route 66 near Weatherford and Hydro, is one of only two upper-story, out-thrust porch style stations left on Oklahoma's stretch of Route 66.

 In 1941, the Hamons family took over the operation of the station and Lucille Hamons, ran the business for 60 years. Lucille, who quickly became known for her friendly assistance to motorists, earned the nickname "Mother of the Mother Road." 

Lucille's Service Station and Roadhouse, in Hydro, Oklahoma Lucille's Service Station and Roadhouse, in Hydro, Oklahoma


Lodging, Dining and Attractions in Weatherford


Weatherford Travel Guide at TripAdvisor

Historic Route 66 in Oklahoma

Hotels in/near Weatherford with traveler reviews at TripAdvisor

Weatherford restaurant listings & reviews at TripAdvisor

Attractions and Things to Do in Weatherford

Interactive Map of Weatherford, Oklahoma

More about Weatherford & Route 66

City of Weatherford website

Weatherford Chamber of Commerce

Weatherford at the TravelOK website

Travel Oklahoma: Route 66

Oklahoma Historical Society: Route 66

Oklahoma Route 66 Association

Weatherford at WeatherUnderground

Weatherford Travel Guide at TripAdvisor

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Weatherford to Texas

Route 66 Road Trip westbound from Oklahoma City to Texas

Oklahoma Route 66 Passport

The Official Oklahoma Route 66 Passport

The Oklahoma Route 66 Passport from the Oklahoma Tourism & Recreation Department helps Route 66 travelers find new destinations to explore and document their progress along the way.

The Route 66 Passport, which is available free at, features 66 of the state’s memorable Mother Road attractions. It includes iconic stops like Catoosa’s Blue Whale, Stroud’s Rock Cafe and Clinton’s Oklahoma Route 66 Museum along with many newer favorites.

Get your passport stamped at each stop, then take it to a Tourism Information Center to be verified and earn an exclusive Route 66 coin.

More information about the Oklahoma Route 66 Passport

Order the Oklahoma Route 66 Passport online